China Baloxavir Marboxil 1985606-14-1 abakhiqizi nabaphakeli

I-Baloxavir Marboxil 1985606-14-1

Incazelo emfushane:

Igama le-API	Inkomba	Umsunguli	Idethi yokuphelelwa yisikhathi kwelungelo lobunikazi(e-US)
I-Baloxavir Marboxil 1985606-14-1	Umkhuhlane	UShionogi noRoche	Sep.21,2031

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

IMINININGWANE YOMKHIQIZO

Ingemuva

I-Baloxavir marboxil iyisidakamizwa esilwa namagciwane futhi iyi-endonuclease inhibitor. Emagundaneni nasezinkawini, ukuhlushwa kwegazi kwesidakamizwa kuphansi kunenani elincane lokutholwa ekuphathweni komlomo okukodwa komuthi. Kumamodeli okutheleleka komkhuhlane we-preclinical A no-B (kuhlanganise nezinhlobo ezimelana nemithi elwa namagciwane ekhona), i-Baloxavir marboxil inomphumela othile.

Chemical Properties

Isitoreji	Gcina ku -20°C
M.Wt	571.55
Cas No.	1985606-14-1
Ifomula	I-C27H23F2N3O7S
Omqondofana	S-033188
Ukuncibilika	I-Soluble ku-DMSO
Igama Lekhemikhali	(((R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8 ,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl)oxy)methyl i-methyl carbonate
I-SDF	Landa i-SDF
I-Canonical SMILES	O=C1C=CN(N([C@]2(N(C3=O)CCOC2)[H])[C@H]4C5=CC=C(C(F)=C5CSC6=CC=CC=C46) F)C3=C1OCOC(OC)=O
Isimo Sokuthumela	Isixazululo sesampula sokuhlola: umkhumbi oneqhwa eliluhlaza. Bonke abanye osayizi abatholakalayo: umkhumbi nge-RT, noma iqhwa eliluhlaza uma uceliwe.
Amathiphu jikelele	Ukuze uthole ukuncibilika okuphezulu, sicela ufudumeze ishubhu ku-37°C bese ulinyakazisa kubhavu we-ultrasonic okwesikhashana. Isixazululo sesitoko singagcinwa ngaphansi -20°C izinyanga ezimbalwa.