I-Thalidomideiyasebenza ekwelapheni lezi zimila!
1. Lapho izimila eziqinile zingasetshenziswa khona i-thalidomide.
1.1.umdlavuza wamaphaphu.
1.2.Umdlavuza wendlala yesinye.
1.3.umdlavuza we-nodal rectal.
1.4.i-hepatocellular carcinoma.
1.5.Umdlavuza wesisu.
2. I-Thalidomide ku-cachexia yesimila
I-oncologic cachexia, isifo somdlavuza esithuthukisiwe esibonakala nge-anorexia, ukuncipha kwezicubu kanye nokuncipha kwesisindo, kuyinselele enkulu ekunakekelweni okupholile komdlavuza othuthukile.
Ngenxa yokusinda okufushane kanye nezinga eliphansi lempilo yeziguli ezinomdlavuza osezingeni eliphezulu, inani lezifundo ezifundweni zemitholampilo lincane, futhi izifundo eziningi ziye zahlola ukusebenza kahle kwesikhathi esiseduze kanye nemiphumela emibi eseduze yesikhathi eside ye-thalidomide, ukusebenza kahle kwesikhathi eside kanye nemiphumela emibi yesikhathi eside ye-thalidomide ekwelapheni i-oncologic cachexia kusadingeka ukuthi ihlolwe ezivivinyweni zomtholampilo ezinosayizi abakhulu besampula.
3. Imiphumela emibi ehlobene nokwelashwa kwe-thalidomide
Ukusabela okubi okufana nokucanuzela kwenhliziyo okuhlobene nokwelashwa ngamakhemikhali kanye nokuhlanza kungase kuthinte ukusebenza kwe-chemotherapy futhi kunciphise izinga lempilo yeziguli.Nakuba abameleli be-neurokinin 1 receptor bangakwazi ukuthuthukisa kakhulu ukusabela okungalungile okufana nokucanuzela kwenhliziyo nokuhlanza, ukusetshenziswa kwabo emtholampilo nokukhuthazwa kunzima ngenxa yesimo sezomnotho seziguli nezinye izizathu.Ngakho-ke, ukufuna umuthi ophephile, osebenzayo futhi oshibhile wokuvimbela nokwelapha isicanucanu nokuhlanza okuhlobene nokwelashwa ngamakhemikhali sekuyinkinga yomtholampilo ephuthumayo.
4. Isiphetho
Ngokuthuthuka okuqhubekayo kocwaningo oluyisisekelo nolwemitholampilo, ukusetshenziswa kwei-thalidomideekwelapheni izimila eziqinile ezivamile bekulokhu kwanda, futhi ukusebenza kwayo emtholampilo nokuphepha kuye kwaqashelwa futhi kwanikezwa amasu amasha okwelapha eziguli.I-Thalidomide iwusizo futhi ekwelapheni i-tumor cachexia kanye nesicanucanu nokuhlanza okuhambisana nokwelashwa ngamakhemikhali.Esikhathini somuthi wokwelapha onembayo, kubalulekile ukuhlola inani labantu abavelele kanye nama-subtypes wesimila asebenzayoi-thalidomideukwelashwa kanye nokuthola ama-biomarker abikezela ukusebenza kwawo kanye nemiphumela emibi.
Isikhathi sokuthumela: Sep-02-2021