I-Thalidomideiyasebenza ekwelapheni lezi zimila!
1. Lapho izimila eziqinile zingasetshenziswa khona i-thalidomide.
1.1. umdlavuza wamaphaphu.
1.2. Umdlavuza wendlala yesinye.
1.3. umdlavuza we-nodal rectal.
1.4. i-hepatocellular carcinoma.
1.5. Umdlavuza wesisu.
2. I-Thalidomide ku-cachexia yesimila
I-oncologic cachexia, isifo somdlavuza esithuthukisiwe esibonakala nge-anorexia, ukuwohloka kwezicubu nokuncipha kwesisindo, kuyinselele enkulu ekunakekelweni kwe-palliative komdlavuza othuthukile.
Ngenxa yokusinda okufushane kanye nezinga lempilo eliphansi leziguli ezinomdlavuza osezingeni eliphezulu, inani lezifundo ezifundweni zomtholampilo lincane, futhi izifundo eziningi zihlole ukusebenza kahle kwesikhathi esiseduze kanye nemiphumela emibi eseduze ye-thalidomide, ukusebenza kahle kwesikhathi eside kanye nemiphumela emibi yesikhathi eside ye-thalidomide ekwelapheni i-oncologic cachexia kusadingeka ukuthi ihlolwe ezivivinyweni zomtholampilo ezinosayizi abakhulu besampula.
3. Imiphumela emibi ehlobene nokwelashwa kwe-thalidomide
Ukusabela okubi okufana nokucanuzela kwenhliziyo okuhlobene nokwelashwa ngamakhemikhali nokuhlanza kungase kuthinte ukusebenza kwe-chemotherapy futhi kunciphise izinga lempilo yeziguli. Nakuba abamelene ne-neurokinin 1 receptor antagonists bangathuthukisa kakhulu ukusabela okungalungile okufana nokucanuzela kwenhliziyo nokuhlanza, ukusetshenziswa kwabo emtholampilo nokukhuthazwa kunzima ngenxa yesimo sezomnotho seziguli nezinye izizathu. Ngakho-ke, ukufuna umuthi ophephile, osebenzayo futhi oshibhile wokuvimbela nokwelapha isicanucanu nokuhlanza okuhlobene ne-chemotherapy sekuyinkinga ephuthumayo yomtholampilo.
4. Isiphetho
Ngokuthuthuka okuqhubekayo kocwaningo oluyisisekelo nolwemitholampilo, ukusetshenziswa kwei-thalidomideekwelapheni izimila eziqinile ezivamile bekulokhu kwanda, futhi ukusebenza kwayo emtholampilo kanye nokuphepha kuye kwaqashelwa futhi kwanikezwa amasu amasha okwelapha eziguli. I-Thalidomide iwusizo futhi ekwelapheni i-tumor cachexia kanye nesicanucanu nokuhlanza okuhambisana nokwelashwa ngamakhemikhali. Esikhathini somuthi wokwelapha onembayo, kubalulekile ukuhlola inani labantu abavelele kanye nama-subtypes wesimila asebenzayoi-thalidomideukwelashwa kanye nokuthola ama-biomarker abikezela ukusebenza kwawo kanye nemiphumela emibi.
Isikhathi sokuthumela: Sep-02-2021