Amaphilisi e-Atorvastatin calcium kanye namaphilisi e-calcium e-rosuvastatin womabili amaphilisi ehlisa i-lipid-lipid, futhi womabili awemithi yama-statin enamandla.Umehluko othize umi kanje:

1. Ngokombono we-pharmacodynamics, uma umthamo ufana, umphumela wokwehlisa i-lipid we-rosuvastatin unamandla kunalowo we-atorvastatin, kodwa kumthamo ojwayelekile onconywe emtholampilo, umphumela wokwehlisa i-lipid wezidakamizwa ezimbili ngokuyisisekelo uyafana. ;

2. Ngokuphathelene nemithi esekelwe ebufakazini, njengoba i-atorvastatin ibilokhu isemakethe ngaphambili, kunobufakazi obuningi be-atorvastatin ezifweni zenhliziyo ne-cerebrovascular kune-rosuvastatin;3. Mayelana ne-metabolism yezidakamizwa, kunomehluko othile phakathi kwalokhu kokubili.I-Atorvastatin igaywa kakhulu yisibindi, kuyilapho ingxenye encane kuphela ye-rosuvastatin igaywa yisibindi.Ngakho-ke, i-atorvastatin ijwayele ukusebenzisana nezidakamizwa okubangelwa ama-enzyme ezidakamizwa zesibindi;

4. I-Atorvastatin ingase ibe nokusabela okungekuhle kwesibindi kune-rosuvastatin.Uma kuqhathaniswa ne-atorvastatin, imiphumela emibi ye-rosuvastatin ingase ibe maningi amathuba okuba yenzeke ezinso.Ngamafuphi, i-atorvastatin ne-rosuvastatin zombili izidakamizwa ezinamandla zokwehlisa i-lipid-lipid, futhi kungase kube nomehluko ekusetshenzisweni kwezidakamizwa, ukusebenzisana kwezidakamizwa, kanye nokusabela okungekuhle.